First, and most importantly, REMOVE ALL DEVICES, WIRES, KEYS, etc. from your SeV. Then, it's easy! 

The Three.0 Leather and the TEC Sport Jacket should be professionally cleaned.

Caring for your leather jacket: Leather is relatively easy to care for if you take preventative measures. Store it so it can breathe (no plastic!), wipe off spills and dirt with a damp cloth. For major cleaning, avoid at-home products (especially waxes and other items that clog up leather pores); find a leather cleaning specialist.

ALL OTHER VERSIONS OF SCOTTEVEST (SeV): FOLLOW INSTRUCTIONS ON THE GARMENT

If the tag on the garment says, "DO NOT DRY CLEAN," you must wash the item. You will ruin the fabric if  you dry clean it. Machine wash in cold water with like colors, delicate cycle recommended. Do not use bleach. Tumble dry LOW, cool iron if necessary. Do not dry flat. Do not steam press.